P187 Matrix metalloproteinases and their inhibitors in sputum of asthmatics (2025)

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Sankaran, P.; Jupp, O.; Jefferson, M.; Sexton, D.; Brockwell, C.; Clark, I.; Wilson, A.

Thorax 68(Suppl 3): A160-A161

2013

ISSN/ISBN: 0040-6376 DOI:10.1136/thoraxjnl-2013-204457.339
Accession:067682003
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P187 Matrix metalloproteinases and their inhibitors in sputum of asthmatics (1)

P187 Matrix metalloproteinases and their inhibitors in sputum of asthmatics (2)


Summary
Introduction and Objectives Metalloproteinases are implicated in the development of airway remodelling in asthma due to their ability to cleave collagen and elastin with extracellular matrix. We optimised a method to purify messenger Ribonucleic acid (m RNA) sputum samples.

References

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P187 Matrix metalloproteinases and their inhibitors in sputum of asthmatics (2025)

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